Provided by: beagle_4.1~180127+dfsg-1_all
Bref - Tool for compressing diploid reference VCF files for the Beagle program.
java -jar /usr/share/beagle/bref.jar [vcf] or java -jar /usr/share/beagle/bref.jar [bref]
Bref is a tool for compressing diploid reference VCF files. Beagle performs genotype calling, genotype phasing, imputation of ungenotyped markers, and identity-by-descent segment detection. Genotypic imputation works on phased haplotypes using a Li and Stephens haplotype frequency model. Beagle also implements the Refined IBD algorithm for detecting homozygosity-by-descent (HBD) and identity-by-descent (IBD) segments.
vcf=filename Creates a .bref file. Specifies a VCF file with phase, non-missing genotype data. If the VCF file is a text file, its filename should end in ".vcf". If the VCF file is GZIP-compressed, its filename should end in ".vcf.gz". bref=filename Prints a .vcf file to standard out. Specifies a binary reference file. The filename should end in ".bref".
Beagle and Bref were written by Brian L. Browning. This manual page was written by Dylan Aïssi <firstname.lastname@example.org>, for the Debian project (but may be used by others).