Provided by: libbio-tools-phylo-paml-perl_1.7.3-4_all
NAME
Bio::Tools::Phylo::PAML::ModelResult - A container for NSSite Model Result from PAML
VERSION
version 1.7.3
SYNOPSIS
# get a ModelResult from a PAML::Result object use Bio::Tools::Phylo::PAML; my $paml = Bio::Tools::Phylo::PAML->new(-file => 'mlc'); my $result = $paml->next_result; foreach my $model ( $result->get_NSSite_results ) { print $model->model_num, " ", $model->model_description, "\n"; print $model->kappa, "\n"; print $model->run_time, "\n"; # if you are using PAML < 3.15 then only one place for POS sites for my $sites ( $model->get_pos_selected_sites ) { print join("\t",@$sites),"\n"; } # otherwise query NEB and BEB slots for my $sites ( $model->get_NEB_pos_selected_sites ) { print join("\t",@$sites),"\n"; } for my $sites ( $model->get_BEB_pos_selected_sites ) { print join("\t",@$sites),"\n"; } }
METHODS
new Title : new Usage : my $obj = Bio::Tools::Phylo::PAML::ModelResult->new(); Function: Builds a new Bio::Tools::Phylo::PAML::ModelResult object Returns : an instance of Bio::Tools::Phylo::PAML::ModelResult Args : -model_num => model number -model_description => model description -kappa => value of kappa -time_used => amount of time -pos_sites => arrayref of sites under positive selection -neb_sites => arrayref of sites under positive selection (by NEB analysis) -beb_sites => arrayref of sites under positive selection (by BEB analysis) -trees => arrayref of tree(s) data for this model -shape_params => hashref of parameters ('shape' => 'alpha', 'gamma' => $g, 'r' => $r, 'f' => $f ) OR ( 'shape' => 'beta', 'p' => $p, 'q' => $q ) -likelihood => likelihood -num_site_classes => number of site classes -dnds_site_classes => hashref with two keys, 'p' and 'w' which each point to an array, each slot is for a different site class. 'w' is for dN/dS and 'p' is probability model_num Title : model_num Usage : $obj->model_num($newval) Function: Get/Set the Model number (0,1,2,3...) Returns : value of model_num (a scalar) Args : on set, new value (a scalar or undef, optional) model_description Title : model_description Usage : $obj->model_description($newval) Function: Get/Set the model description This is something like 'one-ratio', 'neutral', 'selection' Returns : value of description (a scalar) Args : on set, new value (a scalar or undef, optional) time_used Title : time_used Usage : $obj->time_used($newval) Function: Get/Set the time it took to run this analysis Returns : value of time_used (a scalar) Args : on set, new value (a scalar or undef, optional) kappa Title : kappa Usage : $obj->kappa($newval) Function: Get/Set kappa (ts/tv) Returns : value of kappa (a scalar) Args : on set, new value (a scalar or undef, optional) num_site_classes Title : num_site_classes Usage : $obj->num_site_classes($newval) Function: Get/Set the number of site classes for this model Returns : value of num_site_classes (a scalar) Args : on set, new value (a scalar or undef, optional) dnds_site_classes Title : dnds_site_classes Usage : $obj->dnds_site_classes($newval) Function: Get/Set dN/dS site classes, a hashref with 2 keys, 'p' and 'w' which point to arrays one slot for each site class. Returns : value of dnds_site_classes (a hashref) Args : on set, new value (a scalar or undef, optional) get_pos_selected_sites Title : get_pos_selected_sites Usage : my @sites = $modelresult->get_pos_selected_sites(); Function: Get the sites which PAML has identified as under positive selection (w > 1). This returns an array with each slot being a site, 4 values, site location (in the original alignment) Amino acid (I *think* in the first sequence) P (P value) Significance (** indicated > 99%, * indicates >=95%) Returns : Array Args : none add_pos_selected_site Title : add_pos_selected_site Usage : $result->add_pos_selected_site($site,$aa,$pvalue,$signif); Function: Add a site to the list of positively selected sites Returns : count of the number of sites stored Args : $site - site number (in the alignment) $aa - amino acid under selection $pvalue - float from 0->1 represent probability site is under selection according to this model $signif - significance (coded as either empty, '*', or '**' get_NEB_pos_selected_sites Title : get_NEB_pos_selected_sites Usage : my @sites = $modelresult->get_NEB_pos_selected_sites(); Function: Get the sites which PAML has identified as under positive selection (w > 1) using Naive Empirical Bayes. This returns an array with each slot being a site, 4 values, site location (in the original alignment) Amino acid (I *think* in the first sequence) P (P value) Significance (** indicated > 99%, * indicates > 95%) post mean for w Returns : Array Args : none add_NEB_pos_selected_site Title : add_NEB_pos_selected_site Usage : $result->add_NEB_pos_selected_site($site,$aa,$pvalue,$signif); Function: Add a site to the list of positively selected sites Returns : count of the number of sites stored Args : $site - site number (in the alignment) $aa - amino acid under selection $pvalue - float from 0->1 represent probability site is under selection according to this model $signif - significance (coded as either empty, '*', or '**' $postmean - post mean for w get_BEB_pos_selected_sites Title : get_BEB_pos_selected_sites Usage : my @sites = $modelresult->get_BEB_pos_selected_sites(); Function: Get the sites which PAML has identified as under positive selection (w > 1) using Bayes Empirical Bayes. This returns an array with each slot being a site, 6 values, site location (in the original alignment) Amino acid (I *think* in the first sequence) P (P value) Significance (** indicated > 99%, * indicates > 95%) post mean for w (mean) Standard Error for w (SE) Returns : Array Args : none add_BEB_pos_selected_site Title : add_BEB_pos_selected_site Usage : $result->add_BEB_pos_selected_site($site,$aa,$pvalue,$signif); Function: Add a site to the list of positively selected sites Returns : count of the number of sites stored Args : $site - site number (in the alignment) $aa - amino acid under selection $pvalue - float from 0->1 represent probability site is under selection according to this model $signif - significance (coded as either empty, '*', or '**' $postmean - post mean for w $SE - Standard Error for w next_tree Title : next_tree Usage : my $tree = $factory->next_tree; Function: Get the next tree from the factory Returns : L<Bio::Tree::TreeI> Args : none get_trees Title : get_trees Usage : my @trees = $result->get_trees; Function: Get all the parsed trees as an array Returns : Array of trees Args : none rewind_tree_iterator Title : rewind_tree_iterator Usage : $result->rewind_tree_iterator() Function: Rewinds the tree iterator so that next_tree can be called again from the beginning Returns : none Args : none add_tree Title : add_tree Usage : $result->add_tree($tree); Function: Adds a tree Returns : integer which is the number of trees stored Args : L<Bio::Tree::TreeI> shape_params Title : shape_params Usage : $obj->shape_params($newval) Function: Get/Set shape params for the distribution, 'alpha', 'beta' which is a hashref with 1 keys, 'p' and 'q' Returns : value of shape_params (a scalar) Args : on set, new value (a scalar or undef, optional) likelihood Title : likelihood Usage : $obj->likelihood($newval) Function: log likelihood Returns : value of likelihood (a scalar) Args : on set, new value (a scalar or undef, optional)
FEEDBACK
Mailing lists User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to the Bioperl mailing list. Your participation is much appreciated. bioperl-l@bioperl.org - General discussion http://bioperl.org/Support.html - About the mailing lists Support Please direct usage questions or support issues to the mailing list: bioperl-l@bioperl.org rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible. Reporting bugs Report bugs to the Bioperl bug tracking system to help us keep track of the bugs and their resolution. Bug reports can be submitted via the web: https://github.com/bioperl/bio-tools-phylo-paml/issues
AUTHOR
Jason Stajich <jason@bioperl.org>
COPYRIGHT
This software is copyright (c) by Jason Stajich <jason@bioperl.org>. This software is available under the same terms as the perl 5 programming language system itself.